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Greetings! Thank you for your interest in our Center for Pain Therapeutics and Addiction Research (CPTAR). We are a university-wide translational pain and addiction research center that is housed in the School of Dentistry. Our goal is to discover and disseminate novel approaches to prevent and treat pain and addiction. It has been estimated that the annual costs to treat pain (~$600B) and substance misuse (~$800B) in the U.S. keeps rising. Of course, the loss of life and its diminished quality cannot be estimated and represents a major impact on society. Our translational research portfolio ranges from molecular studies to clinical trials and is generated by internationally recognized teams of scientists and clinician-scientists. This occurs via a vibrant and collaborative environment of team science. As a result, our Center is an ideal site for advanced training in pain and substance use disorder along graduate, post-doc or dental scientist/medical scientist career paths. So, please consider joining our effort as a scientist, a trainee or a donor to help mitigate these national crises.