Elizabeth Karpman
Ph.D. Student
About Me
Elizabeth is a PhD student in the Neuroscience discipline of the Integrated Biomedical Sciences program. She attended the University of Rochester, graduating with a dual-degree in 2021. After graduation, Elizabeth worked in the labs of Dr. James Murrough and Dr. Scott Russo at Mount Sinai prior to joining the IBMS program. She is conducting her dissertation research in Dr. Morilak’s lab, where she studies the neural circuitry underlying stress-related psychiatric disorders, with a particular focus on PTSD. Using rat models of stress, Elizabeth combines behavioral techniques with circuit-level approaches to investigate the mechanisms driving heightened startle responses seen in PTSD populations. Her goal is to identify and test novel therapeutic strategies that could help reduce pathological startle reflexes and improve outcomes for individuals with PTSD.
Hobbies/Interests
Hiking, Pilates, Broadway shows, Reading, trying new restaurants
Research Topic
- Establishing the neural circuit responsible for elevated startle responses following chronic unpredictable stress
- Identifying adjunct treatments that combine extinction and pharmacotherapy to relieve fear-elevated startle.
Post-bac work or other affiliations
2021-2024 Laboratory Technician/Research Coordinator, Icahn School of Medicine at Mount Sinai, New York, NY
Education
B.S in Neuroscience and B.A. In Psychology, University of Rochester, 2021
Publications
Aubry, A. V., Durand-de Cuttoli, R., Karpman, E., Fisher-Foye, R. L., Parise, L. F., Cathomas, F., Burnett, C. J., Yang, Y., Yuan, C., LaBanca, A. R., Chan, K. L., Winston, K. T., Lin, H. Y., Dackour, F., Tavallaei, A. A., Alvarez, J., Nishioka, T., Morishita, H., Froemke, R. C., Li, L., … Russo, S. J. (2025). A crucial role for the cortical amygdala in shaping social encounters. Nature, 639(8056), 1006–1015.
Lyu, W., Yin, Z., Xie, L., Pasinetti, G. M., Murrough, J. W., Marchidan, M., Karpman, E., Dobbs, M., Ferruzzi, M. G., Simon, J. E., & Wu, Q. (2024). Method development with high-throughput enhanced matrix removal followed by UHPLC-QqQ-MS/MS for analysis of grape polyphenol metabolites in human urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1242, 124189.